Method of producing substituted benzamides

专利摘要:

公开号:SU1496632A3
申请号:SU864028722
申请日:1986-12-18
公开日:1989-07-23
发明作者:Zhak Asher；Zhan-Klod Mone；Zhan-Pol Shmitt；Rene Gardeks-Lyutro；Brenda Kostal；Rober Nejlor
申请人:Ile De France；
IPC主号:

专利说明:

The invention relates to medicine, namely to gynecology.
The aim of the invention is to prevent side effects from the introduction of drugs.
Example. Patient N., 43 years old, complained of pain in the lower abdomen, sick for 6 years. Diagnosis at admission: uterine fibroids. During the examination, the size of the formation corresponds to an 8-week gestational age, the number of lymphocytes is 1782, T-lymphocytes is 56%, the dopamine content in daily urine is 1453 nmol / day; norepinephrine 163.2 nmol / day, adrenaline 74.2 nmol / day, serotonin 1.82 μmol / L, adaptive training reaction. Appointed: diphenin 2 tablets per day, tincture of Eleutherococcus 20 drops 2 times a day, from the 10th day of the next menstrual cycle dihydroergotamine 15 drops 2 times a day until the 19th day of the cycle inclusive; treatment with diphenin and tincture of Eleutherococcus lasted continuously for 2 months, dihydroergotamine re-added from the 10th day of the second menstrual cycle for 10 days.
After the course of treatment during the examination, the size of the uterus corresponds to a 6-7-week gestation period, there are no pains, the number of lymphocytes is 1830, T-lymphocytes is 62%, the level of excreted dopamine is 1605.1 nmol / day; norepinephrine 136.1 nmol / day, adrenaline 48.3 nmol / day, serotonin 1.1 μmol / L.
The treatment method was tested on 72 patients with various clinical course of uterine fibroids. After treatment, normalization of the psychoemotional state and elimination of pain were established in all patients; a decrease in menstrual blood loss in 94.4%, stabilization and a decrease in the size of the uterus in 95.8% of patients.

权利要求:
Claims (1)
[1]
Claim
511 “149В7НУ
A method of treating uterine fibroids by administering drugs, characterized in that, in order to prevent side effects, diphenin, tincture of Eleutherococcus and dihydroergotamine are administered for two months, while diphenin and tincture of Eleutherococcus are administered daily, and dihydroergotamine in the middle of the menstrual cycle for 10 days.
1496799
Soetavnts.tk, Ί. : [Urysheva

类似技术:

---

公开号 | 公开日 | 专利标题

---

West1932|Curare in man

---

Oppel et al.1950|The effect of pituitary adrenocorticotropin | in dermatomyositis

---

SU1496632A3|1989-07-23|Method of producing substituted benzamides

---

Martin1971|Imipramine pamoate in the treatment of childhood enuresis: a double-blind study

---

Daley et al.1962|Another hypotensive agent—methyldopa

---

Kamman1946|The psychosomatic aspects of sterility

---

SU1496799A1|1989-07-30|Method of treatment of uterus myoma

---

Rachmilewitz et al.1938|Treatment of pellagra with nicotinic acid

---

MARTIN et al.1956|Disseminated actinomycosis treated with tetracycline

---

Barrow et al.1951|The use of purified veratrum viride alkaloids in the treatment of essential hypertension

---

McVAY et al.1951|Streptokinase and streptodornase in the treatment of diabetic gangrene

---

Paoluzi et al.1985|Famotidine | in the treatment of gastric ulcer

---

Godlowski1949|Stimulation of the Suprarenal Glands in the Treatment of Rheumatoid Arthritis: Preliminary Report

---

Bauer et al.1931|Studies of Calcium and Phosphorus Metabolism: X a. The Use of Calcium Chloride to Relieve Peristaltic Pain

---

Elman1943|The oral use of the amino-acids of hydrolyzed casein | in surgical patients

---

Kennedy1959|Case of twin pregnancy in a double uterus

---

Valle et al.2021|Auricular Hematoma in a Dog Treated by Homeopathic Therapy-Case Report

---

Duffy et al.1988|The HELLP syndrome mimics cholecystitis

---

Fava et al.1977|Single Nightly Administration of Ketoprofen | and Indomethacin Suppositories in the Management of Osteoarthritis: A Double-Blind Trial

---

Mulinos1926|Studies on cholin as a motor hormone for the alimentary tract

---

Shimohira et al.1986|Effect of alpha-methyldopa administration during pregnancy on the development of a child's sleep

---

Burnam1912|Corpus luteum extract: with suggestions as to its use in gynecologic practice

---

SU1487907A1|1989-06-23|Method of treating ovular paints

---

RU2132187C1|1999-06-27|Method and magnetic active organic iron compound for treating skin and mucosa disease

---

SU1210847A1|1986-02-15|Method of treatment of patients ill with psoriatic arthritis

同族专利:

---

公开号 | 公开日

---

KR870006008A|1987-07-08|

---

YU217986A|1987-12-31|

---

PH24469A|1990-07-18|

---

PT83982B|1989-01-17|

---

IE863270L|1987-06-19|

---

DK612886D0|1986-12-18|

---

ES2036178T3|1993-05-16|

---

YU44796B|1991-02-28|

---

CS274285B2|1991-04-11|

---

CA1298301C|1992-03-31|

---

DE3674916D1|1990-11-15|

---

DD260495A5|1988-09-28|

---

FI865190A|1987-06-20|

---

CN1018454B|1992-09-30|

---

IL81010A|1991-06-30|

---

EP0236646B1|1990-10-10|

---

HU196794B|1989-01-30|

---

ZM10686A1|1987-11-27|

---

PT83982A|1987-01-01|

---

DK612886A|1987-06-20|

---

AT57376T|1990-10-15|

---

CN86108972A|1987-11-18|

---

CH671396A5|1989-08-31|

---

EP0236646A1|1987-09-16|

---

PL263078A1|1988-04-14|

---

IE59212B1|1994-01-26|

---

AU586057B2|1989-06-29|

---

FI865190A0|1986-12-18|

---

AR242193A1|1993-03-31|

---

OA08564A|1988-09-30|

---

NO865148D0|1986-12-18|

---

GB2184723A|1987-07-01|

---

AU6668786A|1987-06-25|

---

US4914117A|1990-04-03|

---

ZW24886A1|1987-05-13|

---

DE3643103A1|1987-06-25|

---

KR930004653B1|1993-06-02|

---

NO865148L|1987-06-22|

---

IL81010D0|1987-03-31|

---

HUT43844A|1987-12-28|

---

CS960386A2|1990-09-12|

---

MA20835A1|1987-07-01|

---

TNSN86165A1|1990-01-01|

---

PH24365A|1990-06-13|

---

ZA869560B|1987-11-25|

---

GB8630143D0|1987-01-28|

---

US4835172A|1989-05-30|

---

JPS62246553A|1987-10-27|

---

IS3178A7|1987-06-20|

---

PL148408B1|1989-10-31|

---

FR2592042A1|1987-06-26|

---

FR2592042B1|1988-03-25|

---

CA1299579C|1992-04-28|

---

NZ218675A|1990-06-26|

---

GB2184723B|1989-12-28|

---

IN163130B|1988-08-13|

---

NO168176C|1992-01-22|

---

GR3002524T3|1993-01-25|

---

IS1448B6|1991-01-16|

---

NO168176B|1991-10-14|

引用文献:

---

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

---

---

FR4879M|1964-01-13|

---

FR1539104A|1967-07-31|1968-09-13|Ile De France|New benzamides and their preparation process|

---

US3682968A|1969-06-25|1972-08-08|Merck & Co Inc|Anti-inflammatory salicylic acid derivatives|

---

DE1963193A1|1969-12-17|1971-06-24|Bayer Ag|N-substituted 2-arylimino-oxazolidines, process for their preparation and their use as ectoparasiticides|

---

FR2432513B1|1977-10-24|1981-06-12|Merieux Inst|

---

DE2905883A1|1979-02-16|1980-08-28|Boehringer Sohn Ingelheim|Clonidine derivs. contg. tyrosine fragment - useful for radioimmunoassay of antihypertensive clonidine|

---

CA1201066A|1981-11-20|1986-02-25|Alcon Laboratories, Inc.|N-¬3,5-dichloro-4--phenyl|-acetamide solutions for loweringintraocular pressure|

---

US4461904A|1981-11-20|1984-07-24|Alcon Laboratories, Inc.|2--imidazolines|

---

DE3514351A1|1985-04-20|1986-11-06|Boehringer Ingelheim KG, 6507 Ingelheim|NEW SUBSTITUTED 2- AMINO) -IMIDAZOLINE DERIVATIVES, THEIR ACID ADDITIONAL SALTS, THE MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF|

---

JPS6341471A|1986-08-08|1988-02-22|Nippon Soda Co Ltd|Oxazolidine derivative, production thereof and acaricide|

---

US4826990A|1987-09-30|1989-05-02|American Home Products Corporation|2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents|EP0295350B1|1987-06-17|1992-11-11|Laboratoires DELAGRANGE|Use of N-[2-ethyl]-2-methoxy-4-[amino]-5-chlorobenzamide as an anxiolytic and antipsychotic agent|

---

FR2640139A1|1988-12-14|1990-06-15|Delagrange Laboratoires|APPLICATION OF BENZAMIDES SUBSTITUTED AS GASTROMOTORS|

---

FR2640507A1|1988-12-20|1990-06-22|Delagrange Laboratoires|APPLICATION OF BENZAMIDES SUBSTITUTED AS ANXIOLYTICS AND ANTI-PSYCHOTICS|

---

FR2645742A1|1989-04-12|1990-10-19|Delagrange Laboratoires|APPLICATION OF 2-METHOXY 4-AMINO) 5-CHLORO BENZAMIDE DERIVATIVES IN THE TREATMENT OF COGNITIVE FUNCTION DISORDERS|

---

US5401851A|1992-06-03|1995-03-28|Eli Lilly And Company|Angiotensin II antagonists|

---

US20050140688A1|2003-12-29|2005-06-30|Kim Pallister|Method and mechanism for programmable filtering of texture map data in 3D graphics subsystems|

法律状态:

优先权:

---

申请号 | 申请日 | 专利标题

---

FR8518829A|FR2592042B1|1985-12-19|1985-12-19|NOVEL ORTHO-ANISAMIDES, PROCESS FOR OBTAINING THEM, AND THERAPEUTIC APPLICATIONS|

---